FN3K and PCSK6

		FN3K	PCSK6
Description		fructosamine 3 kinase	proprotein convertase subtilisin/kexin type 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Lumen Plasma Membrane Cell Surface Membrane Collagen-containing Extracellular Matrix
	Molecular Function	ATP Binding Kinase Activity Protein-ribulosamine 3-kinase Activity Protein-fructosamine 3-kinase Activity	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Heparin Binding Nerve Growth Factor Binding
	Biological Process	Phosphorylation Fructosamine Metabolic Process Fructoselysine Metabolic Process Epithelial Cell Differentiation Protein Deglycation Post-translational Protein Modification	Zygotic Determination Of Anterior/posterior Axis, Embryo Determination Of Left/right Symmetry Glycoprotein Metabolic Process Protein Processing Peptide Hormone Processing Regulation Of BMP Signaling Pathway Nerve Growth Factor Production Secretion By Cell Regulation Of Lipoprotein Lipase Activity
Pathways		Gamma carboxylation, hypusine formation and arylsulfatase activation	Signaling by NODAL NGF processing Formation of the cornified envelope Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 24647736 34059833 20858683 24244560 31213470 29170429) Hemoglobin A1c levels ( 29403010 31217584) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cytokine levels ( 31679650) Cytokine network levels (multivariate analysis) ( 31679650) Handedness in dyslexia ( 21051773) Height ( 31562340) Inflammatory biomarkers (multivariate analysis) ( 33110245) Platelet-derived growth factor BB levels ( 27989323) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Severe coronary stenosis (young age of onset interaction) ( 33766035) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tuberculosis ( 30713548) Type 2 diabetes ( 30470734)
Interacting Genes		1 interacting genes: PCSK6	12 interacting genes: ALPL CACNA1A FLG FN3K IGF1R IL16 PCSK5 PMCH RCN3 SNRPA1 SYNM ZNF441
Entrez ID		64122	5046
HPRD ID		16336	01329
Ensembl ID		ENSG00000167363	ENSG00000140479
Uniprot IDs		Q9H479	A2RQD9 H7BXT3 P29122 Q59H04
PDB IDs
Enriched GO Terms of Interacting Partners?
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