PCSK6 and RCN3

Number of citations of the paper that reports this interaction (PubMedID 16433634)
15

Data Source:
HPRD (in vivo)

		PCSK6	RCN3
Description		proprotein convertase subtilisin/kexin type 6	reticulocalbin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Lumen Plasma Membrane Cell Surface Membrane Collagen-containing Extracellular Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Intracellular Membrane-bounded Organelle
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Heparin Binding Nerve Growth Factor Binding	Calcium Ion Binding Protein Binding
	Biological Process	Zygotic Determination Of Anterior/posterior Axis, Embryo Determination Of Left/right Symmetry Glycoprotein Metabolic Process Protein Processing Peptide Hormone Processing Regulation Of BMP Signaling Pathway Nerve Growth Factor Production Secretion By Cell Regulation Of Lipoprotein Lipase Activity	Protein Secretion Positive Regulation Of Peptidase Activity Protein Transport Collagen Biosynthetic Process ERAD Pathway Surfactant Homeostasis Regulation Of Protein Kinase B Signaling Phospholipid Homeostasis Lung Epithelium Development
Pathways		Signaling by NODAL NGF processing Formation of the cornified envelope Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cytokine levels ( 31679650) Cytokine network levels (multivariate analysis) ( 31679650) Handedness in dyslexia ( 21051773) Height ( 31562340) Inflammatory biomarkers (multivariate analysis) ( 33110245) Platelet-derived growth factor BB levels ( 27989323) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Severe coronary stenosis (young age of onset interaction) ( 33766035) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tuberculosis ( 30713548) Type 2 diabetes ( 30470734)	Apolipoprotein A1 levels ( 32203549) Fructosamine levels ( 29844224) Height ( 31562340) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Mean spheric corpuscular volume ( 32888494) Schizophrenia ( 25056061) Total glycated albumin levels ( 29844224)
Interacting Genes		12 interacting genes: ALPL CACNA1A FLG FN3K IGF1R IL16 PCSK5 PMCH RCN3 SNRPA1 SYNM ZNF441	13 interacting genes: CCDC103 HID1 KLHL42 MBD3 MKNK1 MYO15B NAA10 PACRGL PCSK6 PRUNE2 STAT6 SUFU ZNF417
Entrez ID		5046	57333
HPRD ID		01329	17962
Ensembl ID		ENSG00000140479	ENSG00000142552
Uniprot IDs		A2RQD9 H7BXT3 P29122 Q59H04	Q96D15
PDB IDs
Enriched GO Terms of Interacting Partners?
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