FIGNL1 and GCC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FIGNL1	GCC1
Description		fidgetin like 1	GRIP and coiled-coil domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Cytoplasm Perinuclear Region Of Cytoplasm Extracellular Exosome	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Microtubule-severing ATPase Activity Hydrolase Activity ATP Hydrolysis Activity	Protein Binding Small GTPase Binding
	Biological Process	Osteoblast Differentiation Male Meiotic Nuclear Division Regulation Of Double-strand Break Repair Via Homologous Recombination Osteoblast Proliferation Negative Regulation Of Apoptotic Process ATP Metabolic Process Microtubule Severing Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 21102463)	Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		8 interacting genes: C1orf112 DMC1 GCC1 IDH1 ITGB1BP1 KDM1A RAD51 SPIDR	73 interacting genes: ABI2 ADGRE5 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 CRHR2 DISC1 DNAJA3 FAM71F2 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX HILPDA ICA1L IKBKG ITSN1 KATNAL1 KDM1A KHSRP KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PCDHA1 PPP1R18 PPP1R27 PRPF18 RBM28 RUNX1 SMARCA2 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 TSC1 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276
Entrez ID		63979	79571
HPRD ID		10958	07599
Ensembl ID		ENSG00000132436	ENSG00000179562
Uniprot IDs		B3KNH6 Q6PIW4	A4D0Z4 Q96CN9
PDB IDs		3D8B
Enriched GO Terms of Interacting Partners?
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