FIGNL1 and DMC1

Number of citations of the paper that reports this interaction (PubMedID 29608566)
22

Data Source:
BioGRID (two hybrid, two hybrid)

		FIGNL1	DMC1
Description		fidgetin like 1	DNA meiotic recombinase 1
Image
GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Cytoplasm Perinuclear Region Of Cytoplasm Extracellular Exosome	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Microtubule-severing ATPase Activity Hydrolase Activity ATP Hydrolysis Activity	DNA Strand Exchange Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Identical Protein Binding
	Biological Process	Osteoblast Differentiation Male Meiotic Nuclear Division Regulation Of Double-strand Break Repair Via Homologous Recombination Osteoblast Proliferation Negative Regulation Of Apoptotic Process ATP Metabolic Process Microtubule Severing Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle
Pathways			Meiotic recombination
Drugs			Imidazole
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 21102463)	Gamma glutamyl transferase levels ( 29403010) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)
Interacting Genes		8 interacting genes: C1orf112 DMC1 GCC1 IDH1 ITGB1BP1 KDM1A RAD51 SPIDR	19 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 LNX1 MSH4 NIF3L1 PIAS2 PICK1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP SDCBP2 TRIM23 UBE2I
Entrez ID		63979	11144
HPRD ID		10958	04099
Ensembl ID		ENSG00000132436	ENSG00000100206
Uniprot IDs		B3KNH6 Q6PIW4	Q14565
PDB IDs		3D8B	1V5W 2ZJB 4HYY 6R3P 7C98 7C99 7C9C 7CGY
Enriched GO Terms of Interacting Partners?
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