GCC1 and ICA1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GCC1	ICA1L
Description		GRIP and coiled-coil domain containing 1	islet cell autoantigen 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol	Golgi Apparatus
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Protein Domain Specific Binding
	Biological Process		Regulation Of Transport
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) Ischemic stroke (small-vessel) ( 29531354) Lacunar stroke ( 33773637) Mean platelet volume ( 32888494) Microalbuminuria ( 31511532) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Platelet count ( 32888494) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) White matter hyperintensities ( 32358547) White matter integrity (fractional anisotropy) ( 32358547)
Interacting Genes		73 interacting genes: ABI2 ADGRE5 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 CRHR2 DISC1 DNAJA3 FAM71F2 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX HILPDA ICA1L IKBKG ITSN1 KATNAL1 KDM1A KHSRP KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PCDHA1 PPP1R18 PPP1R27 PRPF18 RBM28 RUNX1 SMARCA2 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 TSC1 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276	14 interacting genes: DPY30 FAM117B FLACC1 GCC1 HGS KCTD18 KIFC3 KRT27 LMO2 MARS2 MTDH RCOR3 RFTN2 TNPO3
Entrez ID		79571	130026
HPRD ID		07599	12447
Ensembl ID		ENSG00000179562	ENSG00000163596
Uniprot IDs		A4D0Z4 Q96CN9	A0A024R3W3 Q8NDH6 Q96Q33
PDB IDs
Enriched GO Terms of Interacting Partners?
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