SCNN1B and NFASC

Number of citations of the paper that reports this interaction (PubMedID 11470829)
66

Data Source:
HPRD (in vivo)

		SCNN1B	NFASC
Description		sodium channel epithelial 1 subunit beta	neurofascin
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Dendrite Paranodal Junction Node Of Ranvier Axon Initial Segment Schwann Cell Microvillus Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Leukocyte Activation Involved In Inflammatory Response Neutrophil Activation Involved In Immune Response Sodium Ion Transport Excretion Response To Xenobiotic Stimulus Gene Expression Artery Smooth Muscle Contraction Response To Food Aldosterone Metabolic Process Erythrocyte Homeostasis Multicellular Organism Growth Sodium Ion Transmembrane Transport Epithelial Fluid Transport Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Potassium Ion Homeostasis Sodium Ion Homeostasis Mucus Secretion Neutrophil-mediated Killing Of Bacterium Urea Homeostasis Cellular Response To Aldosterone	Cell Adhesion Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Myelination Synapse Organization Protein Localization To Plasma Membrane
Pathways		Stimuli-sensing channels	Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation
Drugs		Triamterene Amiloride
Diseases
GWAS		Kidney stones ( 31729369)	Age at first sexual intercourse ( 34211149) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576 29875488 28240269) Clozapine-induced agranulocytosis ( 25187353) Dental caries ( 23064961) Diisocyanate-induced asthma ( 25918132) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) General risk tolerance (MTAG) ( 30643258) High myopia ( 32428537) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Regular attendance at a religious group ( 29970889)
Interacting Genes		14 interacting genes: ANK3 CNTN1 COMMD10 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2	12 interacting genes: ABI1 ABI2 ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR
Entrez ID		6338	23114
HPRD ID		02861	12372
Ensembl ID		ENSG00000168447	ENSG00000163531
Uniprot IDs		B2R812 P51168	B4DRH7 O94856
PDB IDs		6BQN 6WTH	3P3Y 3P40
Enriched GO Terms of Interacting Partners?
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