NFASC and SCNN1B

Number of citations of the paper that reports this interaction (PubMedID 11470829)
66

Data Source:
HPRD (in vivo)

		NFASC	SCNN1B
Description		neurofascin	sodium channel epithelial 1 subunit beta
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Dendrite Paranodal Junction Node Of Ranvier Axon Initial Segment Schwann Cell Microvillus Ficolin-1-rich Granule Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process	Cell Adhesion Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Myelination Synapse Organization Protein Localization To Plasma Membrane	Leukocyte Activation Involved In Inflammatory Response Neutrophil Activation Involved In Immune Response Sodium Ion Transport Excretion Response To Xenobiotic Stimulus Gene Expression Artery Smooth Muscle Contraction Response To Food Aldosterone Metabolic Process Erythrocyte Homeostasis Multicellular Organism Growth Sodium Ion Transmembrane Transport Epithelial Fluid Transport Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Potassium Ion Homeostasis Sodium Ion Homeostasis Mucus Secretion Neutrophil-mediated Killing Of Bacterium Urea Homeostasis Cellular Response To Aldosterone
Pathways		Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation	Stimuli-sensing channels
Drugs			Triamterene Amiloride
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576 29875488 28240269) Clozapine-induced agranulocytosis ( 25187353) Dental caries ( 23064961) Diisocyanate-induced asthma ( 25918132) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) General risk tolerance (MTAG) ( 30643258) High myopia ( 32428537) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Regular attendance at a religious group ( 29970889)	Kidney stones ( 31729369)
Interacting Genes		12 interacting genes: ABI1 ABI2 ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR	14 interacting genes: ANK3 CNTN1 COMMD10 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2
Entrez ID		23114	6338
HPRD ID		12372	02861
Ensembl ID		ENSG00000163531	ENSG00000168447
Uniprot IDs		B4DRH7 O94856	B2R812 P51168
PDB IDs		3P3Y 3P40	6BQN 6WTH
Enriched GO Terms of Interacting Partners?
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