RRM2 and LPIN1

		RRM2	LPIN1
Description		ribonucleotide reductase regulatory subunit M2	lipin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Ribonucleoside-diphosphate Reductase Complex	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane
	Molecular Function	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Ferric Iron Binding Protein Homodimerization Activity	Transcription Coactivator Activity Protein Binding Phosphatidate Phosphatase Activity
	Biological Process	Blastocyst Development DNA Replication Deoxyribonucleotide Biosynthetic Process Protein Heterotetramerization	DNA Replication Triglyceride Mobilization Phosphatidic Acid Biosynthetic Process Mitotic Nuclear Membrane Disassembly Fatty Acid Catabolic Process Dephosphorylation Triglyceride Biosynthetic Process Animal Organ Regeneration Negative Regulation Of Myelination Cellular Response To Insulin Stimulus Cellular Lipid Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cold-induced Thermogenesis Regulation Of Phosphatidate Phosphatase Activity
Pathways		Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6	Synthesis of PC Synthesis of PE Depolymerisation of the Nuclear Lamina Triglyceride biosynthesis
Drugs		Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)	Chronotype ( 30696823) Metabolite levels ( 23823483) Post bronchodilator percent predicted FEV1 in smoking ( 30068317)
Interacting Genes		19 interacting genes: ASAP2 BARX1 CDH1 CDK1 DNM1L GCG ITSN2 KAT5 LAPTM4A LPIN1 MGAT4A NPBWR2 PLK3 RRM1 RRM2B SDCBP ST3GAL3 TAF1B TP53	2 interacting genes: CDK6 RRM2
Entrez ID		6241	23175
HPRD ID		01587	09271
Ensembl ID		ENSG00000171848	ENSG00000134324
Uniprot IDs		P31350	Q14693
PDB IDs		2UW2 3OLJ 3VPM 3VPN 3VPO
Enriched GO Terms of Interacting Partners?
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