ARHGAP22 and ALG11

		ARHGAP22	ALG11
Description		Rho GTPase activating protein 22	ALG11 alpha-1,2-mannosyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion Glutamatergic Synapse	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activator Activity Protein Binding	Alpha-1,2-mannosyltransferase Activity GDP-Man:Man3GlcNAc2-PP-Dol Alpha-1,2-mannosyltransferase Activity
	Biological Process	Angiogenesis Signal Transduction Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity Regulation Of Postsynapse Organization	Protein N-linked Glycosylation Oligosaccharide-lipid Intermediate Biosynthetic Process Mannosylation
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS		Conduct disorder ( 20585324) Daytime sleep phenotypes ( 27126917) Diabetic retinopathy ( 21310492) Macular thickness ( 30535121) Refractive error ( 32231278) Self-employment ( 23593239) Systolic blood pressure ( 31134134) Systolic blood pressure (education interaction) ( 31134134)
Interacting Genes		13 interacting genes: ALG11 CACNA1A CCNDBP1 CDC42 DEF6 FXR1 GPRIN2 IL1RAPL1 MAPK8 PTPN20 RAC1 RHOA ZNF488	1 interacting genes: ARHGAP22
Entrez ID		58504	440138
HPRD ID		12476	11265
Ensembl ID		ENSG00000128805	ENSG00000253710
Uniprot IDs		A0A2X0SFC0 Q7Z5H3	Q2TAA5
PDB IDs
Enriched GO Terms of Interacting Partners?
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