ARHGAP22 and IL1RAPL1

Number of citations of the paper that reports this interaction (PubMedID 21926414)
44

Data Source:
BioGRID (pull down)

		ARHGAP22	IL1RAPL1
Description		Rho GTPase activating protein 22	interleukin 1 receptor accessory protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion Glutamatergic Synapse	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Axon Dendrite Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity Protein Binding	Signaling Receptor Binding Protein Binding Interleukin-1 Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating
	Biological Process	Angiogenesis Signal Transduction Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity Regulation Of Postsynapse Organization	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Exocytosis Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Presynaptic Membrane Assembly Regulation Of Postsynapse Organization Trans-synaptic Signaling By Trans-synaptic Complex Regulation Of Presynapse Assembly
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle	Receptor-type tyrosine-protein phosphatases Interleukin-38 signaling
Drugs
Diseases
GWAS		Conduct disorder ( 20585324) Daytime sleep phenotypes ( 27126917) Diabetic retinopathy ( 21310492) Macular thickness ( 30535121) Refractive error ( 32231278) Self-employment ( 23593239) Systolic blood pressure ( 31134134) Systolic blood pressure (education interaction) ( 31134134)	Cardiovascular risk factors (age interaction) ( 20838585) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Vitiligo ( 27723757)
Interacting Genes		13 interacting genes: ALG11 CACNA1A CCNDBP1 CDC42 DEF6 FXR1 GPRIN2 IL1RAPL1 MAPK8 PTPN20 RAC1 RHOA ZNF488	3 interacting genes: ARHGAP22 NCS1 POLA1
Entrez ID		58504	11141
HPRD ID		12476	02193
Ensembl ID		ENSG00000128805	ENSG00000169306
Uniprot IDs		A0A2X0SFC0 Q7Z5H3	Q9NZN1 X5DNQ7
PDB IDs			1T3G 4M92 5WY8
Enriched GO Terms of Interacting Partners?
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