DHX37 and MIRLET7E

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		DHX37	MIRLET7E
Description		DEAH-box helicase 37	microRNA let-7e
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleoplasm Nucleolus Cytoplasm Nuclear Membrane	Extracellular Space
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity U3 SnoRNA Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Brain Development Ribosome Biogenesis Ribosome Assembly Positive Regulation Of Male Gonad Development	Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Signaling Receptor Activity
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference ( 28552196) Insulin levels in response to oral glucose tolerance test (120 minutes) ( 29093273)
Interacting Genes		55 interacting genes: ATXN1 KIFAP3 KRT31 MIR1-1 MIR1-2 MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR143 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR29A MIR34A MIR34B MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PLXNA2 RGS17 TRIP6	105 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RBM47 RBM5 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		57647	406887
HPRD ID		10883
Ensembl ID		ENSG00000150990	ENSG00000198972
Uniprot IDs		Q8IY37
PDB IDs
Enriched GO Terms of Interacting Partners?
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