MIRLET7E and XAB2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIRLET7E	XAB2
Description		microRNA let-7e	XPA binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Prp19 Complex Nucleus Nucleoplasm Membrane Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding
	Biological Process	Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Signaling Receptor Activity	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Blastocyst Development Transcription-coupled Nucleotide-excision Repair Transcription, DNA-templated Cerebral Cortex Development
Pathways			Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		105 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RBM47 RBM5 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346	17 interacting genes: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 MIR106B MIR34B MIRLET7E MIRLET7G MIRLET7I POLR2A PPIE SMAD9 SUMO2 XPA
Entrez ID		406887	56949
HPRD ID			18306
Ensembl ID		ENSG00000198972	ENSG00000076924
Uniprot IDs			Q9HCS7
PDB IDs			5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7ABI
Enriched GO Terms of Interacting Partners?
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