DHX37 and MIR451A

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		DHX37	MIR451A
Description		DEAH-box helicase 37	microRNA 451a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleoplasm Nucleolus Cytoplasm Nuclear Membrane	Extracellular Space Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity U3 SnoRNA Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Brain Development Ribosome Biogenesis Ribosome Assembly Positive Regulation Of Male Gonad Development	Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transporter Activity Gene Silencing By MiRNA Positive Regulation Of Vascular Wound Healing Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference ( 28552196) Insulin levels in response to oral glucose tolerance test (120 minutes) ( 29093273)	Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		55 interacting genes: ATXN1 KIFAP3 KRT31 MIR1-1 MIR1-2 MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR143 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR29A MIR34A MIR34B MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PLXNA2 RGS17 TRIP6	76 interacting genes: AIMP1 AIMP2 APOBEC3B AQR C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		57647	574411
HPRD ID		10883
Ensembl ID		ENSG00000150990	ENSG00000284565
Uniprot IDs		Q8IY37
PDB IDs
Enriched GO Terms of Interacting Partners?
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