AGPAT4 and LRRC25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AGPAT4	LRRC25
Description		1-acylglycerol-3-phosphate O-acyltransferase 4	leucine rich repeat containing 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane	Cytoplasm Integral Component Of Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Acyltransferase Activity	Protein Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways		Synthesis of PA
Drugs
Diseases
GWAS		Anxiety in major depressive disorder ( 24047446) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Fear of pain ( 28701861) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Metabolite levels ( 23823483)	Body size at age 10 ( 32376654) Hyperemesis gravidarum ( 29563502) Monocyte percentage of white cells ( 32888494 27863252) Severity of nausea and vomiting of pregnancy ( 29563502) Systemic lupus erythematosus ( 33536424 28714469) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: AQP12B AQP6 CNR2 CREB3L1 ERGIC3 FCGR2A FCRL3 FFAR2 GPR101 HSD17B11 HSD17B13 JAGN1 LEPROTL1 LEUTX LRRC25 MFF MFSD14B MGST3 REEP4 REL RETREG3 SCN3B SLC35C2 SLC7A8 SPACA1 TMEM14B TMEM31 TMX2	38 interacting genes: ACD AGPAT4 ANKRD46 APOL3 ATP6V0C BMP10 BRICD5 C3orf52 CD72 CLDN19 CLEC1A CLN6 CLRN2 CNIH3 CXCL9 DEFB121 DNAJC30 EDDM3B FAM3C FATE1 FPR2 GPRC5D LHFPL5 MAL OPRM1 PKMYT1 PNLIPRP1 SEC22A SEC61G SMCO4 SPNS3 TMEM120A TMEM201 TNF TRAF3IP3 TSPAN4 VAMP5 YIPF6
Entrez ID		56895	126364
HPRD ID		12437	09597
Ensembl ID		ENSG00000026652	ENSG00000175489
Uniprot IDs		Q9NRZ5	Q8N386
PDB IDs
Enriched GO Terms of Interacting Partners?
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