AGPAT4 and SPACA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AGPAT4	SPACA1
Description		1-acylglycerol-3-phosphate O-acyltransferase 4	sperm acrosome associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane	Inner Acrosomal Membrane Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Acyltransferase Activity	Protein Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process	Acrosome Assembly
Pathways		Synthesis of PA
Drugs
Diseases
GWAS		Anxiety in major depressive disorder ( 24047446) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Fear of pain ( 28701861) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Metabolite levels ( 23823483)	Echocardiographic traits ( 17903301) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		28 interacting genes: AQP12B AQP6 CNR2 CREB3L1 ERGIC3 FCGR2A FCRL3 FFAR2 GPR101 HSD17B11 HSD17B13 JAGN1 LEPROTL1 LEUTX LRRC25 MFF MFSD14B MGST3 REEP4 REL RETREG3 SCN3B SLC35C2 SLC7A8 SPACA1 TMEM14B TMEM31 TMX2	25 interacting genes: AGPAT4 ATP6V0B ATP6V0C BNIP3 CACNG7 CD72 CLDN19 CTXN3 EMP1 EMP3 GIMAP5 LSMEM2 NRSN1 NSG1 PLN PMP22 RPRM SERP2 SERTM1 SGCG SMAGP SMIM3 THSD7B TMEM140 TMEM47
Entrez ID		56895	81833
HPRD ID		12437	15419
Ensembl ID		ENSG00000026652	ENSG00000118434
Uniprot IDs		Q9NRZ5	Q9HBV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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