RPRM and COQ8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RPRM	COQ8A
Description		reprimo, TP53 dependent G2 arrest mediator homolog	coenzyme Q8A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding
	Biological Process	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		79 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22	26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 LDAF1 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM239 TPD52L2
Entrez ID		56475	56997
HPRD ID		18002	07375
Ensembl ID		ENSG00000177519	ENSG00000163050
Uniprot IDs		Q9NS64	Q8NI60
PDB IDs			4PED 5I35
Enriched GO Terms of Interacting Partners?
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