RPRM and KCNJ6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RPRM	KCNJ6
Description		reprimo, TP53 dependent G2 arrest mediator homolog	potassium inwardly rectifying channel subfamily J member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Protein Binding	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Recurrent major depressive disorder x sex interaction ( 34099189)	Body size at age 10 ( 32376654) Clostridioides difficle infection ( 33841421) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)
Interacting Genes		79 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22	64 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RPS6KA2 RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24
Entrez ID		56475	3763
HPRD ID		18002	02929
Ensembl ID		ENSG00000177519	ENSG00000157542
Uniprot IDs		Q9NS64	P48051
PDB IDs
Enriched GO Terms of Interacting Partners?
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