YEATS2 and DR1

Number of citations of the paper that reports this interaction (PubMedID 22939629)
326

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology, biochemical)

		YEATS2	DR1
Description		YEATS domain containing 2	down-regulator of transcription 1
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GO Annotations	Cellular Component	Mitotic Spindle	Nucleoplasm Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding TBP-class Protein Binding Histone Binding Modification-dependent Protein Binding	Core Promoter Sequence-specific DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Histone H3 Acetylation Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Adult body size ( 32376654) Systolic blood pressure ( 30224653) Visceral fat ( 30942860)	Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 32203549) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Red blood cell count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549 29403010 33339817) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: DR1 TBP	9 interacting genes: DNMT3L DRAP1 NFIL3 NFYC POLE3 TBP XPO1 YEATS2 ZDHHC17
Entrez ID		55689	1810
HPRD ID		07652	03284
Ensembl ID		ENSG00000163872	ENSG00000117505
Uniprot IDs		Q9ULM3	Q01658 Q658N3
PDB IDs		5IQL 5XNV 6LSD	1JFI
Enriched GO Terms of Interacting Partners?
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