GPRC5D and APOL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPRC5D	APOL3
Description		G protein-coupled receptor class C group 5 member D	apolipoprotein L3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Extracellular Region Cytoplasm Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Lipid Transporter Activity Lipid Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity	Lipid Transport Inflammatory Response Lipoprotein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Total intracranial volume ( 31530798)
Interacting Genes		31 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERC1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	28 interacting genes: ELOVL4 FATE1 FXYD6-FXYD2 GJA8 GJB1 GJB5 GJC1 GPR152 GPRC5D HAS3 IL7R LHFPL5 LINC00839 LRRC25 MFSD6 NCALD PMP22 RNF19B SGCB SLC16A2 SLC1A5 SLC7A14 STX1A TIMMDC1 TMEM167B TMEM237 TMEM52B TNFRSF10D
Entrez ID		55507	80833
HPRD ID		07604	06264
Ensembl ID		ENSG00000111291	ENSG00000128284
Uniprot IDs		Q9NZD1	A0A024R1G6 O95236
PDB IDs
Enriched GO Terms of Interacting Partners?
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