GPRC5D and TMEM120B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPRC5D	TMEM120B
Description		G protein-coupled receptor class C group 5 member D	transmembrane protein 120B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Cellular_component Nuclear Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Molecular_function Ion Channel Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity	Biological_process Fat Cell Differentiation Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 24026423 32888494 27863252) Mean reticulocyte volume ( 32888494) Molybdenum levels ( 26025379) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		31 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERC1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	58 interacting genes: ALOX5AP ANKS6 APOA5 AQP6 AQP8 BNIP3L CCNDBP1 CD74 COMT CPLX4 CREB3L1 DNAH10 EBP ERGIC3 FCER1G FFAR2 FKBP7 GAD2 GJB1 GORAB GPR152 GPRC5D GPX8 HSD17B11 IFNGR2 IL7R JAGN1 JPH1 KCNJ6 LMNA LRRTM2 MGST3 MRPS18B MTRFR MUC1 NCAPH2 REEP2 REEP4 RETREG3 RNF19B RNF5 SCN3B SH3GL3 SLC10A1 SLC10A6 SLC17A8 SLC18A1 SLC1A3 STOM STX2 TLCD4 TMEM139 TMEM143 TMEM14B TMEM80 TMPRSS2 TMX2 ZDHHC15
Entrez ID		55507	144404
HPRD ID		07604	19119
Ensembl ID		ENSG00000111291	ENSG00000188735
Uniprot IDs		Q9NZD1	A0PK00
PDB IDs
Enriched GO Terms of Interacting Partners?
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