GPRC5D and MS4A6A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPRC5D	MS4A6A
Description		G protein-coupled receptor class C group 5 member D	membrane spanning 4-domains A6A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Trans-Golgi Network Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease ( 21460840) Alzheimer's disease (late onset) ( 30617256 24162737 28714976) Alzheimer's disease in APOE e4- carriers ( 25778476) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) C-reactive protein levels ( 30388399) Cerebrospinal fluid sTREM-2 levels ( 31708768) Factor VII activity ( 30642921) Factor VII activity or levels ( 30642921) Family history of Alzheimer's disease ( 30617256) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422 26561523) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549 28869591) Lymphocyte percentage of white cells ( 32888494) Methadone dose in opioid dependence ( 28115739) Neutrophil count ( 32888494) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		31 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERC1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	2 interacting genes: GPRC5D ZDHHC5
Entrez ID		55507	64231
HPRD ID		07604	09414
Ensembl ID		ENSG00000111291	ENSG00000110077
Uniprot IDs		Q9NZD1	A0A024R516 A0A024R554 B4DUN6 E9PSA9 Q9H2W1
PDB IDs
Enriched GO Terms of Interacting Partners?
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