UBA6 and UBE2G2

Number of citations of the paper that reports this interaction (PubMedID 17597759)
139

Data Source:
BioGRID (pull down)

		UBA6	UBE2G2
Description		ubiquitin like modifier activating enzyme 6	ubiquitin conjugating enzyme E2 G2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Ubiquitin Activating Enzyme Activity Protein Binding ATP Binding FAT10 Activating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Learning Locomotory Behavior Protein Ubiquitination Amygdala Development Hippocampus Development Protein Modification By Small Protein Conjugation Dendritic Spine Development	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)	Alanine aminotransferase levels ( 33547301)
Interacting Genes		16 interacting genes: HMBOX1 JUNB LMO2 OTUB1 SMAD9 UBC UBD UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2L3 UBE2L6 UBE2S UBE2T UBE2Z	41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		55236	7327
HPRD ID		13341	04387
Ensembl ID		ENSG00000033178	ENSG00000184787
Uniprot IDs		A0AVT1 A1LT96	P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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