LIME1 and TBRG4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LIME1	TBRG4
Description		Lck interacting transmembrane adaptor 1	transforming growth factor beta regulator 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex	Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule
	Molecular Function	Protein Binding Protein Kinase Binding	RNA Binding Protein Binding
	Biological Process	Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling	Mitochondrial RNA Processing Positive Regulation Of Cell Population Proliferation MRNA Metabolic Process Regulation Of Mitochondrial MRNA Stability Regulation Of Cell Cycle Mitochondrial MRNA Processing
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein A1 levels ( 33730874) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Bell's palsy ( 33602968) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Colorectal cancer or advanced adenoma ( 30510241) Plateletcrit ( 32888494)
Interacting Genes		46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1	24 interacting genes: AGTRAP BICD2 BSND CALCOCO2 CDR2L CMTM4 CMTM5 FAM114A2 FAM9B GPRASP2 HSD17B13 KRT27 LIME1 MAL2 MEOX2 PRB3 PTN RETREG3 SCAMP1 SFT2D1 STK19 TFIP11 TMEM239 TNFRSF10D
Entrez ID		54923	9238
HPRD ID		07904	10263
Ensembl ID		ENSG00000203896	ENSG00000136270
Uniprot IDs		A0A087WT39 Q9H400	B3KM73 B3KRS4 B4DU42 Q969Z0
PDB IDs
Enriched GO Terms of Interacting Partners?
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