LIME1 and NINJ1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LIME1	NINJ1
Description		Lck interacting transmembrane adaptor 1	ninjurin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex	Extracellular Region Integral Component Of Membrane Synaptic Membrane
	Molecular Function	Protein Binding Protein Kinase Binding	Lipopolysaccharide Binding Protein Binding Cell Adhesion Mediator Activity
	Biological Process	Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling	Angiogenesis Leukocyte Chemotaxis Involved In Inflammatory Response Cell Adhesion Nervous System Development Programmed Cell Death Cytolysis Heterotypic Cell-cell Adhesion Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Tissue Regeneration Muscle Cell Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Inflammatory Response Protein Homooligomerization Necrotic Cell Death
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein A1 levels ( 33730874) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Bell's palsy ( 33602968) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Lactate dehydrogenase levels ( 29403010) Liver enzyme levels (alanine transaminase) ( 33972514) Obesity (early onset extreme) ( 23563609)
Interacting Genes		46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1	20 interacting genes: AQP6 CD200R1 CEACAM3 CREB3L1 CYB5R3 EBP FCGR1A FNDC9 GOLM1 GPX8 HIVEP1 KRT40 LIME1 MUC1 PVR SGCB TIMMDC1 TLCD4 TMEM14B TMEM31
Entrez ID		54923	4814
HPRD ID		07904	03639
Ensembl ID		ENSG00000203896	ENSG00000131669
Uniprot IDs		A0A087WT39 Q9H400	Q92982
PDB IDs
Enriched GO Terms of Interacting Partners?
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