LIME1 and MEST

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LIME1	MEST
Description		Lck interacting transmembrane adaptor 1	mesoderm specific transcript
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding Hydrolase Activity
	Biological Process	Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling	Mesoderm Development Regulation Of Lipid Storage
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein A1 levels ( 33730874) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Bell's palsy ( 33602968) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1	24 interacting genes: APP BAG6 BLOC1S2 C6orf47 CD300C CEP70 CIAO2A CIDEB CMTM3 CRELD2 DBN1 FBXO7 FEZ1 FST GAD2 HGS ING5 IRF5 KIFAP3 LIME1 MPZL2 RNF19B ZNF205 ZNF579
Entrez ID		54923	4232
HPRD ID		07904	06776
Ensembl ID		ENSG00000203896	ENSG00000106484
Uniprot IDs		A0A087WT39 Q9H400	A0A024R768 A4D1L9 B4DQW6 Q5EB52
PDB IDs
Enriched GO Terms of Interacting Partners?
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