RNF216 and MORC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RNF216	MORC3
Description		ring finger protein 216	MORC family CW-type zinc finger 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Schaffer Collateral - CA1 Synapse Postsynaptic Endocytic Zone Glutamatergic Synapse	Nucleoplasm Nuclear Matrix PML Body
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Apoptotic Process Negative Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Defense Response To Virus By Host Protein K48-linked Ubiquitination Protein Catabolic Process, Modulating Synaptic Transmission	Protein Phosphorylation Cell Aging Post-embryonic Development Peptidyl-serine Phosphorylation Negative Regulation Of Fibroblast Proliferation Protein Stabilization Maintenance Of Protein Location In Nucleus
Pathways		Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)	Diastolic blood pressure ( 30224653) Height ( 31562340)
Interacting Genes		30 interacting genes: AGFG1 BRCA1 CAPN15 FAM168A KIR2DL4 MAPK1 MORC3 OPTN RIPK1 RNF11 SUMO2 TLR3 TLR4 TLR5 TLR9 TNFAIP3 TRAF3 UBAC1 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L3 UBE2L6 USP5 YOD1 ZFAND2A	12 interacting genes: ERCC6 GALNT1 HOOK3 KPNA2 RNF216 SEC61B SETD4 SUMO2 SUMO3 TBX1 UBC ZBTB32
Entrez ID		54476	23515
HPRD ID		15550	10316
Ensembl ID		ENSG00000011275	ENSG00000159256
Uniprot IDs		A8K8N1 Q9NWF9	B4DHJ4 Q14149 Q4VBZ9
PDB IDs			4QQ4 5SVI 5SVX 5SVY 6O1E 6O5W
Enriched GO Terms of Interacting Partners?
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