MIEF1 and MED21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIEF1	MED21
Description		mitochondrial elongation factor 1	mediator complex subunit 21
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Integral Component Of Membrane	Ubiquitin Ligase Complex Mediator Complex
	Molecular Function	Protein Binding GDP Binding Identical Protein Binding ADP Binding	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitochondrial Fission Mitochondrial Fusion Cellular Response To Hypoxia Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Stem Cell Population Maintenance RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways			PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 32888494)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG	30 interacting genes: BLOC1S6 BORCS6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HGS HNF4A HTT MAGEA6 MAGEB4 MED29 MIEF1 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 TRIM72 VAV2 ZNF655 ZSCAN1
Entrez ID		54471	9412
HPRD ID		13371	09156
Ensembl ID		ENSG00000100335	ENSG00000152944
Uniprot IDs		A0A024R1L3 B0QY95 Q9H0J7 Q9NQG6	A0A024RAW0 Q13503
PDB IDs		4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
Enriched GO Terms of Interacting Partners?
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