MIEF1 and CMTM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIEF1	CMTM6
Description		mitochondrial elongation factor 1	CKLF like MARVEL transmembrane domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane Early Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Protein Binding GDP Binding Identical Protein Binding ADP Binding	Protein Binding
	Biological Process	Mitochondrial Fission Mitochondrial Fusion Cellular Response To Hypoxia Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane	Protein Transport Regulation Of Protein Stability Endocytic Recycling
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 32888494)	Apolipoprotein B levels ( 32203549) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Cholesterol, total ( 24097068) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG	24 interacting genes: APOA5 ATP13A2 BPIFA2 CD160 CD40 CIAO2A COQ8A DNMT3B DUSP10 DYNC1LI1 ECPAS EHHADH FAM9B MIEF1 PPBP RBFA RBMX RUSC1 SNRPB2 SPG21 SUMO2 TCEA2 TMED8 XRCC6
Entrez ID		54471	54918
HPRD ID		13371	06987
Ensembl ID		ENSG00000100335	ENSG00000091317
Uniprot IDs		A0A024R1L3 B0QY95 Q9H0J7 Q9NQG6	Q9NX76
PDB IDs		4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
Enriched GO Terms of Interacting Partners?
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