MIEF1 and ABHD5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIEF1	ABHD5
Description		mitochondrial elongation factor 1	abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Integral Component Of Membrane	Nucleoplasm Mitochondrion Lipid Droplet Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding GDP Binding Identical Protein Binding ADP Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Protein Binding Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Mitochondrial Fission Mitochondrial Fusion Cellular Response To Hypoxia Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Lipid Homeostasis
Pathways			Triglyceride catabolism
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 32888494)	Body shape index ( 34021172) General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG	21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12
Entrez ID		54471	51099
HPRD ID		13371	11986
Ensembl ID		ENSG00000100335	ENSG00000011198
Uniprot IDs		A0A024R1L3 B0QY95 Q9H0J7 Q9NQG6	A0A0S2Z5D6 Q8WTS1
PDB IDs		4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
Enriched GO Terms of Interacting Partners?
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