PLAC8 and FCHO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLAC8	FCHO1
Description		placenta associated 8	FCH and mu domain containing endocytic adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Azurophil Granule Lumen	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Chromatin Binding	Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis	Clathrin Coat Assembly Clathrin-dependent Endocytosis
Pathways		Neutrophil degranulation	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		QRS interval (sulfonylurea treatment interaction) ( 27958378)	Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		24 interacting genes: BAG4 C19orf54 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 TEX37 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX	52 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GDF15 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688
Entrez ID		51316	23149
HPRD ID		06335	16887
Ensembl ID		ENSG00000145287	ENSG00000130475
Uniprot IDs		Q9NZF1 X2BQ60	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs
Enriched GO Terms of Interacting Partners?
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