MYBL1 and NCL

Number of citations of the paper that reports this interaction (PubMedID 10660576)
26

Data Source:
BioGRID (affinity chromatography technology, far western blotting)
HPRD (in vitro, in vivo)

		MYBL1	NCL
Description		MYB proto-oncogene like 1	nucleolin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nucleolus Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Male Meiosis I Spermatogenesis Negative Regulation Of Transposition Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II PiRNA Biosynthetic Process	Angiogenesis Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Leukemia Inhibitory Factor
Pathways		PIWI-interacting RNA (piRNA) biogenesis	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Hearing loss in noise exposure ( 26121033) Height ( 31562340) Hip index ( 34021172)
Interacting Genes		4 interacting genes: CREBBP HIPK2 NCL NLK	57 interacting genes: ADAP1 ADAP2 CD3E CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 DUX4 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R LINC01554 MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 OGT PARP1 PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 S100A11 SREK1 SRPK2 SSB STAU1 SUMO2 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZFP41 ZNF689
Entrez ID		4603	4691
HPRD ID		08868	01245
Ensembl ID		ENSG00000185697	ENSG00000115053
Uniprot IDs		P10243 Q495G0	B3KM80 P19338
PDB IDs			2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?
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