NCL and SSB

Number of citations of the paper that reports this interaction (PubMedID 12096904)
29

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		NCL	SSB
Description		nucleolin	small RNA binding exonuclease protection factor La
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nucleolus Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex	Chromosome, Telomeric Region Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding	TRNA Binding RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Sequence-specific MRNA Binding
	Biological Process	Angiogenesis Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Leukemia Inhibitory Factor	TRNA 5'-leader Removal TRNA Modification TRNA Export From Nucleus TRNA Processing Histone MRNA Metabolic Process TRNA 3'-end Processing Nuclear Histone MRNA Catabolic Process IRES-dependent Viral Translational Initiation Protein Localization To Cytoplasmic Stress Granule
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Hearing loss in noise exposure ( 26121033) Height ( 31562340) Hip index ( 34021172)	Common carotid intima-media thickness in HIV infection ( 29206233) Fasting glucose change (long-term) ( 31263163) Glomerular filtration rate in diabetes ( 29703844)
Interacting Genes		57 interacting genes: ADAP1 ADAP2 CD3E CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 DUX4 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R LINC01554 MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 OGT PARP1 PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 S100A11 SREK1 SRPK2 SSB STAU1 SUMO2 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZFP41 ZNF689	13 interacting genes: APP CDC42 CSNK2A1 CSNK2B GZMH HMGA1 IL7R NAT8 NCL OGT PTEN SPIB SPP1
Entrez ID		4691	6741
HPRD ID		01245	00168
Ensembl ID		ENSG00000115053	ENSG00000138385
Uniprot IDs		B3KM80 P19338	P05455
PDB IDs		2FC8 2FC9 2KRR	1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
Enriched GO Terms of Interacting Partners?
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