Description |
methionine sulfoxide reductase A |
COP9 signalosome subunit 5 |
Image |
No pdb structure |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adiposity ( 19557161)
- Adult body size ( 32376654)
- Age at first sexual intercourse ( 27089180)
- Alzheimer's disease ( 20452100)
- Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218)
- Autoimmune thyroid disease ( 32581359)
- Barrett's esophagus ( 27527254)
- Barrett's esophagus or Esophageal adenocarcinoma ( 27527254)
- Bipolar disorder ( 31043756)
- Bipolar disorder and schizophrenia ( 22688191)
- BMI x environmental factors (excluding physical activity) interaction ( 33654129)
- Body mass index ( 30108283 31453325)
- Body mass index variance ( 31453325)
- Body shape index ( 34021172)
- Body size at age 10 ( 32376654)
- Brain morphology (MOSTest) ( 32665545)
- Bulimia nervosa ( 23568457)
- Chronotype ( 26835600)
- Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
- Cooked vegetable consumption ( 32066663)
- Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
- Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
- Depression ( 33859377)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 27863252)
- Estimated glomerular filtration rate ( 31152163)
- Feeling worry ( 29500382)
- Fish- and plant-related diet ( 32066663)
- Fruit consumption ( 32066663)
- General factor of neuroticism ( 30867560)
- General risk tolerance (MTAG) ( 30643258)
- Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
- Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
- HDL cholesterol levels ( 32203549)
- Hypertension ( 19430479)
- Insomnia ( 32332799)
- Insomnia symptoms (never/rarely vs. usually) ( 30804566)
- Irritable mood ( 29500382)
- Joint mobility (Beighton score) ( 27182965)
- Liver enzyme levels (alanine transaminase) ( 33972514)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401)
- Medication use (diuretics) ( 31015401)
- Medication use (thyroid preparations) ( 31015401)
- Myopia (pathological) ( 23049088)
- Neurociticism ( 29500382)
- Nose size ( 27182965)
- Obesity (early onset extreme) ( 20421936)
- Oily fish consumption ( 32066663)
- Plasma kynurenine to tryptophan ratio in major depressive disorder ( 29317604)
- Pork consumption ( 32066663)
- Processed meat consumption ( 32066663)
- Pulse pressure ( 30578418)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Raw vegetable consumption ( 32066663)
- Refractive error ( 32231278)
- Remission after SSRI treatment in MDD or neuroticism ( 29559929)
- Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
- Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
- Schizophrenia ( 28991256 21679298 30285260 26198764)
- Serum metabolite levels ( 33031748)
- Smoking initiation (ever regular vs never regular) ( 30679032)
- Systemic lupus erythematosus ( 28714469)
- Systolic blood pressure ( 30224653 30578418)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- TPE interval (resting) ( 32386560)
- Triglyceride levels ( 32203549)
- Type 2 diabetes ( 30297969)
- Waist circumference ( 30108283)
- Waist circumference adjusted for body mass index ( 34021172)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172)
- Weight ( 30108283)
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Interacting Genes |
14 interacting genes:
ARID2
CCNI
COPB2
COPS5
CTNNA3
EFCAB11
FARSB
FBXL3
HPCAL4
HSPA4L
P4HA3
SDHB
SELENBP1
WDR44
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99 interacting genes:
APCS
ARFGAP1
ATM
ATRN
BCL2L14
BCL3
BRD4
BRSK2
CACNA1C
CD274
CD93
CDKN1B
CENPT
COPS2
COPS3
COPS4
COPS6
COPS7A
COPS7B
COPS8
COPS9
CUL1
CUL2
CUL3
CUL4A
CUL4B
CUL5
DDB1
DDO
ERN1
ERRFI1
ESR1
F2RL1
GFER
GFI1B
GPS1
GTPBP3
HAND2
HIF1A
HNF4A
HNF4G
HTR6
IKBKB
ITGB2
JUN
JUND
LASP1
MAP2K2
MAP3K11
MAP3K3
MAP3K7
MAP4K3
MAP4K5
MAPK14
MAPRE1
MAX
MDC1
MDM2
MEF2C
MEF2D
MIF
MSRA
MTRES1
MYG1
NCOA1
NEDD8
NFKB1
NR4A2
NR4A3
OPRM1
PEA15
PGR
PLAC8
PPARG
PPOX
PPP1CC
PRDX2
PRKD1
PTGS2
RAD1
RAD9A
RNF139
RORA
S100A7
SHANK3
SHISA5
SMAD2
SMAD4
SMAD5
SPP1
SREBF2
TOP2A
TP53
TXN
TYK2
UCHL1
VTN
WNK1
YWHAG
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Entrez ID |
4482 |
10987 |
HPRD ID |
03152 |
06888 |
Ensembl ID |
ENSG00000175806
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ENSG00000121022
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Uniprot IDs |
Q9UJ68
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A0A024R7W9
Q92905
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PDB IDs |
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4D10
4D18
4F7O
4WSN
5JOG
5JOH
5M5Q
6R6H
6R7F
6R7H
6R7I
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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