MSR1 and NKG7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		MSR1	NKG7
Description		macrophage scavenger receptor 1	natural killer cell granule protein 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Low-density Lipoprotein Particle	Lysosome Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Amyloid-beta Binding Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding Cargo Receptor Activity	Protein Binding
	Biological Process	Receptor-mediated Endocytosis Phagocytosis, Engulfment Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Storage Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Transport Cellular Response To Organic Cyclic Compound Amyloid-beta Clearance
Pathways		Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Blood protein levels ( 23696881) HDL cholesterol levels in HIV infection ( 33109212) Hip circumference adjusted for BMI ( 28552196) Neurological blood protein biomarker levels ( 31320639) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		8 interacting genes: ADRB2 ATP6V0C FA2H HSPA1A LEPROTL1 MALL NKG7 SEC22A	47 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 PLEKHF2 PRRG2 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88
Entrez ID		4481	4818
HPRD ID		01092	16188
Ensembl ID		ENSG00000038945	ENSG00000105374
Uniprot IDs		P21757	Q16617
PDB IDs
Enriched GO Terms of Interacting Partners?
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