MSR1 and LEPROTL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		MSR1	LEPROTL1
Description		macrophage scavenger receptor 1	leptin receptor overlapping transcript like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Low-density Lipoprotein Particle	Endosome Integral Component Of Membrane
	Molecular Function	Amyloid-beta Binding Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding Cargo Receptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Receptor-mediated Endocytosis Phagocytosis, Engulfment Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Storage Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Transport Cellular Response To Organic Cyclic Compound Amyloid-beta Clearance	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Pathways		Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Blood protein levels ( 23696881) HDL cholesterol levels in HIV infection ( 33109212) Hip circumference adjusted for BMI ( 28552196) Neurological blood protein biomarker levels ( 31320639) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: ADRB2 ATP6V0C FA2H HSPA1A LEPROTL1 MALL NKG7 SEC22A	74 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MFSD14B MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 PPP3CC RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35C2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15
Entrez ID		4481	23484
HPRD ID		01092	09551
Ensembl ID		ENSG00000038945	ENSG00000104660
Uniprot IDs		P21757	O95214 Q6FHL7
PDB IDs
Enriched GO Terms of Interacting Partners?
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