MSR1 and SEC22A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		MSR1	SEC22A
Description		macrophage scavenger receptor 1	SEC22 homolog A, vesicle trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Low-density Lipoprotein Particle	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Amyloid-beta Binding Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding Cargo Receptor Activity	Transporter Activity Protein Binding
	Biological Process	Receptor-mediated Endocytosis Phagocytosis, Engulfment Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Storage Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Transport Cellular Response To Organic Cyclic Compound Amyloid-beta Clearance	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport
Pathways		Scavenging by Class A Receptors Scavenging by Class A Receptors	COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Blood protein levels ( 23696881) HDL cholesterol levels in HIV infection ( 33109212) Hip circumference adjusted for BMI ( 28552196) Neurological blood protein biomarker levels ( 31320639) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		8 interacting genes: ADRB2 ATP6V0C FA2H HSPA1A LEPROTL1 MALL NKG7 SEC22A	106 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDAF1 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC14A2 SLC30A2 SLC35C2 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27
Entrez ID		4481	26984
HPRD ID		01092	15313
Ensembl ID		ENSG00000038945	ENSG00000121542
Uniprot IDs		P21757	Q96IW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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