MNDA and MAPK8IP2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
26

Data Source:
BioGRID (two hybrid)

		MNDA	MAPK8IP2
Description		myeloid cell nuclear differentiation antigen	mitogen-activated protein kinase 8 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Nucleolus Cytosol Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Postsynaptic Density Protein-containing Complex Neuronal Cell Body
	Molecular Function	Double-stranded DNA Binding Protein Binding	Amyloid-beta Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	Activation Of Innate Immune Response Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway	Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Signaling Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Excitatory Postsynaptic Potential Regulation Of NMDA Receptor Activity Regulation Of AMPA Receptor Activity Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)	Cutaneous leishmaniasis ( 32830257) Gut microbiota relative abundance (Prevotella) ( 33208821) Hip circumference ( 28552196)
Interacting Genes		14 interacting genes: CDK1 CDK2 CRK DPCD FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53	85 interacting genes: ADRB2 AFG3L2 ANAPC10 APP ASRGL1 BBS10 C1QTNF3 C22orf39 C8orf33 CFL1 CHN1 CRMP1 CRP CTNNBL1 DUSP16 DUSP18 EGFR ERBB2 ERG28 EZH2 FGF12 FGF13 FSCN1 GALNT3 GBP2 HLA-C HOXC8 IGIP ING4 ITSN1 KIFC2 KLC1 LEFTY2 LRP1 LRP2 LRP8 LSM8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 MNDA MRE11 MSRB3 NDUFS6 NUMB PLXNA3 POLR1H PRSS23 RAI1 RBM4 RBX1 RPS6KB2 RYBP SCLT1 SH2D1B SLC39A13 SLPI SMARCB1 SMS SPINK2 SPSB3 SRP19 SYNE2 TARBP2 TIAM1 TMEM128 TP53BP2 UNC119 USP46 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF670 ZNF784
Entrez ID		4332	23542
HPRD ID		15932	09674
Ensembl ID		ENSG00000163563	ENSG00000008735
Uniprot IDs		P41218 Q5VUU6	Q13387
PDB IDs		2DBG 5H7Q 5WPZ
Enriched GO Terms of Interacting Partners?
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