MNDA and NSD3

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		MNDA	NSD3
Description		myeloid cell nuclear differentiation antigen	nuclear receptor binding SET domain protein 3
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GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Nucleolus Cytosol Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Ficolin-1-rich Granule Lumen	Chromatin Nucleus Nucleoplasm
	Molecular Function	Double-stranded DNA Binding Protein Binding	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Activation Of Innate Immune Response Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways		Neutrophil degranulation	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)
Interacting Genes		14 interacting genes: CDK1 CDK2 CRK DPCD FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53	49 interacting genes: AKT1 AP3M2 ATM BCAR3 BMP8B CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 E2F5 ESR1 ETV3 ETV6 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 IVNS1ABP LSM1 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 SQSTM1 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		4332	54904
HPRD ID		15932	06155
Ensembl ID		ENSG00000163563	ENSG00000147548
Uniprot IDs		P41218 Q5VUU6	Q9BZ95
PDB IDs		2DBG 5H7Q 5WPZ	2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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