MLLT6 and UBE2G2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MLLT6	UBE2G2
Description		MLLT6, PHD finger containing	ubiquitin conjugating enzyme E2 G2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding Nucleosome Binding Histone Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Sodium Ion Transport Negative Regulation Of Urine Volume Renal Sodium Excretion Renal Potassium Excretion Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K79 Methylation	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301)
Interacting Genes		26 interacting genes: APP CASK CEBPE CEBPG CEP44 CREB5 CRX ENOX2 GRIPAP1 IKBKG KRTAP10-8 MED15 MEOX2 NSD3 PHC2 PIN1 SPRY2 TCF12 TCF4 TLE5 TNFRSF4 UBE2G2 UBQLN1 UBQLN4 ZBTB22 ZMYND19	41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		4302	7327
HPRD ID		08978	04387
Ensembl ID		ENSG00000275023	ENSG00000184787
Uniprot IDs		P55198	P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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