C4orf3 and PLEKHO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C4orf3	PLEKHO1
Description		chromosome 4 open reading frame 3	pleckstrin homology domain containing O1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane
	Molecular Function		Protein Binding
	Biological Process	Negative Regulation Of Calcium Ion Binding Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis Regulation Of Myoblast Fusion
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		67 interacting genes: ADGRG3 AQP2 AQP6 ARL13B BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 DEGS1 EBP ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MFSD14B MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PTGES REEP4 RETREG3 RHBDL1 RHCG SERINC2 SHISAL1 SLC14A2 SLC19A3 SLC35C2 SLC35E3 SLC39A2 SLC41A3 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A	40 interacting genes: ADAM33 ADAMTSL4 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C1orf56 C4orf3 CDC42SE1 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB GOLPH3L IFI35 LRP10 MMD NAPB OGT PSMC5 RPRD2 RPS20 SMAD5 SMG5 SMURF1 SYT11 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1
Entrez ID		401152	51177
HPRD ID		14223	12217
Ensembl ID		ENSG00000164096	ENSG00000023902
Uniprot IDs		Q8WVX3	Q53GL0 Q5T4P9
PDB IDs			3AA1
Enriched GO Terms of Interacting Partners?
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