C4orf3 and ADGRG3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C4orf3	ADGRG3
Description		chromosome 4 open reading frame 3	adhesion G protein-coupled receptor G3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Specific Granule Membrane
	Molecular Function		G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Calcium Ion Binding Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway B Cell Differentiation Regulation Of Cell Migration Negative Regulation Of CREB Transcription Factor Activity Negative Regulation Of NIK/NF-kappaB Signaling
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)
Interacting Genes		67 interacting genes: ADGRG3 AQP2 AQP6 ARL13B BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 DEGS1 EBP ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MFSD14B MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PTGES REEP4 RETREG3 RHBDL1 RHCG SERINC2 SHISAL1 SLC14A2 SLC19A3 SLC35C2 SLC35E3 SLC39A2 SLC41A3 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A	12 interacting genes: ATP6V0B C3orf52 C4orf3 CTXN3 GIMAP5 LHFPL5 PLP1 RPRM SEC22A TEX264 UPK2 VSTM1
Entrez ID		401152	222487
HPRD ID		14223	17073
Ensembl ID		ENSG00000164096	ENSG00000182885
Uniprot IDs		Q8WVX3	B4DVW2 F8W8F7 Q86Y34
PDB IDs
Enriched GO Terms of Interacting Partners?
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