PLEKHO1 and TSPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHO1	TSPO2
Description		pleckstrin homology domain containing O1	translocator protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Organelle Membrane
	Molecular Function	Protein Binding	Protein Binding Cholesterol Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis Regulation Of Myoblast Fusion	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Amino Acid Import Across Plasma Membrane Import Across Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)
Interacting Genes		40 interacting genes: ADAM33 ADAMTSL4 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C1orf56 C4orf3 CDC42SE1 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB GOLPH3L IFI35 LRP10 MMD NAPB OGT PSMC5 RPRD2 RPS20 SMAD5 SMG5 SMURF1 SYT11 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	59 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM RSPH9 SLC10A1 SLC10A6 SLC16A2 SLC34A2 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR
Entrez ID		51177	222642
HPRD ID		12217	16569
Ensembl ID		ENSG00000023902	ENSG00000112212
Uniprot IDs		Q53GL0 Q5T4P9	Q5TGU0
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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