SLC18A1 and TMEM42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC18A1	TMEM42
Description		solute carrier family 18 member A1	transmembrane protein 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Terminal Bouton Clathrin-sculpted Monoamine Transport Vesicle Membrane	Integral Component Of Membrane
	Molecular Function	Serotonin:sodium Symporter Activity Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Protein Binding
	Biological Process	Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Xenobiotic Transport Serotonin Uptake Transmembrane Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters
Drugs		Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cholesterol ( 31902109) Coronary artery disease ( 30104761) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Hypertriglyceridemia ( 23505323) Major depressive disorder (broad) ( 20038947) Metabolic syndrome ( 30382898 31589552) Persistent hepatitis B virus infection ( 27244555) Pulse pressure ( 27841878) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Triglyceride levels in HIV infection ( 33109212) Triglycerides ( 18193046 24886709)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756)
Interacting Genes		61 interacting genes: AGTRAP ANKRD46 APOL2 BRICD5 C2CD2L CCL4 CCL4L2 CNIH1 COL4A5 CTSA CXCL16 CYB561D2 FAM3C FCER1G FXYD3 GIMAP1 GJB2 GPR151 LAT MALL MFSD6 MGAM MIP MS4A1 MS4A13 NEU1 NRM OLFM4 ORMDL1 PEX16 PLP1 PLP2 PMP22 PNLIPRP1 PPP3CC RPRM SLC30A2 SLC30A8 SLC35B4 SLC35G1 SLC38A7 SLC39A2 SMCO4 SMIM1 STX2 STX8 TFRC TMEM120B TMEM128 TMEM14A TMEM14B TMEM203 TMEM218 TMEM239 TMEM42 TMEM60 TMEM65 TMEM86A VAMP5 YIPF4 YIPF6	54 interacting genes: AQP3 AQP6 BDKRB1 CD79A DTX2 EBP EDA ELOVL4 ERGIC3 FAM174A FAM209A GET1 GJA8 GOLM2 GPR152 GPX8 HSD17B11 HSD17B13 LEPROTL1 LHFPL5 LMNA MFF MGAT5B MMD MMGT1 MRM1 MTIF3 NEMP1 PROP1 PSCA RABAC1 RBPMS REEP1 REEP2 RETREG3 RHBDD1 SAR1A SCN3B SEC11C SERINC2 SHISAL1 SLC18A1 SLC34A2 SMIM14 SVOPL TLX3 TM4SF19 TMEM147 TMEM14B TMEM237 TMEM35A TMEM74 VENTX ZDHHC15
Entrez ID		6570	131616
HPRD ID		01897	15540
Ensembl ID		ENSG00000036565	ENSG00000169964
Uniprot IDs		P54219 Q96GL6	Q69YG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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