ANKS6 and BCL2L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ANKS6	BCL2L2
Description		ankyrin repeat and sterile alpha motif domain containing 6	BCL2 like 2
Image
GO Annotations	Cellular Component	Cytoplasm Ciliary Inversin Compartment	Mitochondrial Outer Membrane Cytosol Bcl-2 Family Protein Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding Disordered Domain Specific Binding
	Biological Process	In Utero Embryonic Development Kidney Development Determination Of Left/right Symmetry Heart Development	Response To Ischemia Spermatogenesis Brain Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Apoptotic Process Sertoli Cell Proliferation Cellular Response To Estradiol Stimulus Negative Regulation Of Release Of Cytochrome C From Mitochondria Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Amyloid-beta Cellular Response To Glycine Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs			Navitoclax
Diseases
GWAS		Body mass index ( 28892062)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		20 interacting genes: AGTRAP APP BCL2L2 BET1 C1GALT1 C5 EMD EMP1 IGFBP5 MARCHF5 MFSD14C PITPNC1 RTP2 SMIM1 STRIT1 STX7 TMEM120B TMEM60 VAMP4 VEZT	53 interacting genes: ANKS6 APOC1 APOC2 APOC4 ATP5PF BAD BAK1 BAX BBC3 BCL2L11 BHLHA9 BID BIK BMF BNIP3 BNIP5 C10orf67 CD79A CHODL CIDEB CISD2 CLDN7 ERVFRD-1 FATE1 G0S2 GORAB GPR151 GPX8 HRK KASH5 KCNJ6 LMNA LRRIQ1 MGST2 MUC1 PANX1 PPP1CA PSCA RHBDD2 S100B SAR1A SGPL1 SLC35C2 SLC35E3 SLC39A2 SLC39A6 STOM SUSD3 TCF4 TEX11 TMEM139 TMX1 TP53
Entrez ID		203286	599
HPRD ID		18012	03569
Ensembl ID		ENSG00000165138	ENSG00000129473
Uniprot IDs		B3KXP1 Q68DC2	Q92843
PDB IDs		4NL9	1MK3 1O0L 1ZY3 2Y6W 4CIM
Enriched GO Terms of Interacting Partners?
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