KLK1 and SERPINC1

Number of citations of the paper that reports this interaction (PubMedID 3643793)
29

Data Source:
BioGRID (pull down)

		KLK1	SERPINC1
Description		kallikrein 1	serpin family C member 1
Image
GO Annotations	Cellular Component	Nucleus Secretory Granule Extracellular Exosome	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Serine-type Endopeptidase Activity	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Zymogen Activation	Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Regulation Of Blood Coagulation, Intrinsic Pathway
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Aluminium Benzamidine Lanoteplase Aprotinin Aniline Nafamostat Aluminium phosphate Aluminum acetate	Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human
Diseases
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)	Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)
Interacting Genes		8 interacting genes: A2M ITIH4 KNG1 PROC SERPINA1 SERPINA4 SERPINA5 SERPINC1	14 interacting genes: ATP1B1 CHML CREG1 F2 FMO3 HSP90AA1 KLK1 KLK2 KLK6 MRPS14 PIGC PLG QSOX1 SDC2
Entrez ID		3816	462
HPRD ID		01003	00122
Ensembl ID		ENSG00000167748	ENSG00000117601
Uniprot IDs		A0A1L2BPJ2 A0A1R3UCD2 P06870	A0A024R944 P01008
PDB IDs		1SPJ	1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1
Enriched GO Terms of Interacting Partners?
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