ITGA5 and LGALS3BP

Number of citations of the paper that reports this interaction (PubMedID 24362527)
14

Data Source:
BioGRID (pull down)

		ITGA5	LGALS3BP
Description		integrin subunit alpha 5	galectin 3 binding protein
Image
GO Annotations	Cellular Component	Ruffle Plasma Membrane Cell-cell Junction Focal Adhesion Integrin Complex Cell Surface Ruffle Membrane Integrin Alpha5-beta1 Complex Alphav-beta3 Integrin-vitronectin Complex	Extracellular Region Extracellular Space Membrane Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Virus Receptor Activity Platelet-derived Growth Factor Receptor Binding Protein Binding Vascular Endothelial Growth Factor Receptor 2 Binding Metal Ion Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Angiogenesis Cell Adhesion Integrin-mediated Signaling Pathway CD40 Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-substrate Adhesion Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Wound Healing, Spreading Of Epidermal Cells Endodermal Cell Differentiation Viral Entry Into Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Sprouting Angiogenesis Negative Regulation Of Anoikis	Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction
Pathways		Elastic fibre formation Fibronectin matrix formation Cell surface interactions at the vascular wall Integrin cell surface interactions Integrin cell surface interactions Signal transduction by L1 RUNX2 regulates genes involved in cell migration	Platelet degranulation
Drugs		Resveratrol
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 30072576)
Interacting Genes		33 interacting genes: ANGPT1 ANGPT2 ANGPTL3 ARHGAP5 AUP1 CD9 CHMP2A CLK1 COL18A1 COL1A1 EGFR ERBB2 FGFR2 FLT4 FN1 GIPC1 GPR182 GRK6 ITGB1 ITGB3 ITGB5 L1CAM LGALS3BP NISCH PECAM1 RABIF SHARPIN SPP1 STAMBP THAP1 TNC UBAP1 VCL	24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		3678	3959
HPRD ID		00627	02796
Ensembl ID		ENSG00000161638	ENSG00000108679
Uniprot IDs		B2R627 P08648	A0A0S2Z3Y1 Q08380
PDB IDs		3VI3 3VI4 4WJK 4WK0 4WK2 4WK4	1BY2 6GFB
Enriched GO Terms of Interacting Partners?
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