IL3RA and C2CD2L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IL3RA	C2CD2L
Description		interleukin 3 receptor subunit alpha	C2CD2 like
Image
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex	Endoplasmic Reticulum Membrane Integral Component Of Membrane Cortical Endoplasmic Reticulum Cytoplasmic Side Of Apical Plasma Membrane Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding	Protein Binding Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Insulin Binding
	Biological Process	Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway	Phospholipid Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Intermembrane Lipid Transfer
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs		Sargramostim Tagraxofusp
Diseases
GWAS		Schizophrenia ( 17522711)	Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549)
Interacting Genes		32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5	32 interacting genes: AQP6 ARL13B ATP5MG CD79A CHODL CISD2 CLRN1 CPEB2 CXCR3 EBP EPB41 FCER1G GJA8 GJB1 HIBADH IL3RA MFSD5 MUC1 OPRM1 PDZK1IP1 REEP2 REEP4 SDCBP SLC10A6 SLC18A1 TMEM14B TMEM179B TMEM31 TMEM86B TMEM9 TMPRSS2 TMX2
Entrez ID		3563	9854
HPRD ID		02392	15533
Ensembl ID		ENSG00000185291	ENSG00000172375
Uniprot IDs		P26951	O14523
PDB IDs		4JZJ 5UV8 5UWC 6NMY	5TOD
Enriched GO Terms of Interacting Partners?
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