IL3RA and SYS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IL3RA	SYS1
Description		interleukin 3 receptor subunit alpha	SYS1 golgi trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex	Trans-Golgi Network Cytosol Integral Component Of Golgi Membrane Trans-Golgi Network Membrane
	Molecular Function	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding	Protein Binding
	Biological Process	Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway	Golgi To Endosome Transport Protein Localization To Golgi Apparatus Golgi To Plasma Membrane Protein Transport
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling	Retrograde transport at the Trans-Golgi-Network
Drugs		Sargramostim Tagraxofusp
Diseases
GWAS		Schizophrenia ( 17522711)	Free cholesterol levels in large HDL ( 29084231) Large HDL particle concentration ( 29084231) Malaria ( 31844061) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231)
Interacting Genes		32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5	20 interacting genes: BTNL9 EBP ELOVL5 ERGIC3 FCER1G GLP1R HSD17B11 IL3RA KIR3DL3 MCFD2 MGST3 MRPS18B PSCA PVR SDCBP SLC30A8 SLC35C2 TM4SF19 TMEM248 TNFSF14
Entrez ID		3563	90196
HPRD ID		02392
Ensembl ID		ENSG00000185291	ENSG00000204070
Uniprot IDs		P26951	Q8N2H4
PDB IDs		4JZJ 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?
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