H1-2 and HELLS

Number of citations of the paper that reports this interaction (PubMedID 33288900)
2

Data Source:
BioGRID (pull down)

		H1-2	HELLS
Description		H1.2 linker histone, cluster member	helicase, lymphoid specific
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Euchromatin Nucleus Transcriptionally Active Chromatin	Chromosome, Centromeric Region Nucleus Pericentric Heterochromatin
	Molecular Function	Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding	Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Nucleosome Assembly Nucleosome Positioning Chromosome Condensation Negative Regulation Of DNA Recombination Histone H3-K4 Trimethylation Histone H3-K27 Trimethylation	Urogenital System Development DNA Methylation DNA Methylation-dependent Heterochromatin Assembly Cell Cycle Multicellular Organism Development Maintenance Of DNA Methylation Pericentric Heterochromatin Assembly Lymphocyte Proliferation Cell Division Cellular Response To Leukemia Inhibitory Factor Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS			Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Red cell distribution width ( 32888494) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Serum alkaline phosphatase levels ( 33547301) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes		29 interacting genes: AEBP2 APP ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 HELLS IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 SNCA VHL WDR12 YBX1	10 interacting genes: APP DNMT1 DNMT3B E2F3 GPAT4-AS1 GTSF1L H1-2 HDAC1 MEOX2 SERTAD2
Entrez ID		3006	3070
HPRD ID		07514	07232
Ensembl ID		ENSG00000187837	ENSG00000119969
Uniprot IDs		P16403	A0A087WSW7 A0A0B4J1V9 F6XU50 Q0VGL2 Q76H82 Q9NRZ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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