PILRA and PAICS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PILRA	PAICS
Description		paired immunoglobin like type 2 receptor alpha	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding MHC Class I Protein Binding	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding
	Biological Process	Signal Transduction	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Purine ribonucleoside monophosphate biosynthesis
Drugs			Aspartic acid
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red cell distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: DNPH1 FAM114A2 FCAR PAICS PFDN5 PTPN11 PTPN6 SORBS1 TOM1 UROD	21 interacting genes: CDC37 CEP76 CHD3 FXR1 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 PTPRC RAD54L2 RNF4 SMARCD1 TERF1 UBE2I UBE3A ZMYM2
Entrez ID		29992	10606
HPRD ID		05631	01401
Ensembl ID		ENSG00000085514	ENSG00000128050
Uniprot IDs		Q9UKJ1	P22234
PDB IDs		3WUZ 3WV0 4NFB 5XO2 5XOF	2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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